CPM Seminar

Nanoelectronic sensors for biological molecules

Delphine Bouilly

Institute for Research in Immunology and Cancer (IRIC) & Département de physique, Université de Montréal

Our research focuses on the design and application of ultraminiaturized electrical circuits able to capture and probe biological molecules such as DNA and proteins. Such nanosensors allow us to follow, through alterations in the circuit electrical conductance, successive chemical reactions and conformational changes occurring on ensemble or isolated biomolecules. I will present recent high-resolution nanofabrication strategies for assembling such sensors using carbon nanotubes and graphene, as well as experiments based on this approach to explore the conformational and hybridization dynamics of DNA sequences. Finally, I will discuss our plans to expand this emerging technique towards studying fundamental mechanisms in biomolecules and for labona-chip biomedical technology.